Call your endo again! I don't understand how they think she is keeping her Cortef down if she is vomiting. She isn't keeping it down. If it were my son, I would give the shot. I wrote the message board about this same subject. How long do you wait, how fast can a crisis happen, etc. EVERYONE told me "When in doubt, inject.!!" A crisis can happen quickly especially when they are vomiting.The lethargy (tiredness) is a sign that she needs help. Call your endo again.Andrea