Thanks for responding to my posting. I think that it is interesting that both our girls have high levels of 17 OHP and display this kind of behaviour. Unfortunately, I have had no luck getting information from her endo. He says that they see high levels of this in many cases and they used to increase cortisone to lower it; however, now they don't. She has therefore not her doses increased for fear that it could alter her bone growth which is now at the perfect stage. I have been firm with her but nothing seems to work. Time-outs don't mean anything, nor does going to her room. Most of the time it's for hitting, but all others are signs of aggression as well. I am concerned that this behaviour will be a problem next year when she goes to school. I feel badly because she's so sweet, but if she continues like this she won't have any friends. Do you have any suggestions? It seems that her endo doesn't relate the two - he says she is just becoming familiar with her surroundings. She's 3, I may have accepted that answer 2 yrs ago but I feel that I have to do something to help her. Thanks, Angela