I appreciate the advice but I thought I should clarify a few things for those of you who may think that I am some kind of monster who would rather see my children suffer than ease thier pain and make them well. My son is the stronger of the two CAH children that I have. I have been told by 3 endocrinologists, that the solu-cortef should be given if they are vomiting the medicine up when it is given orally. I called and checked with the pediatrician and the endocrinologist who both said to continue giving the meds to my son orally, if he could handle it and he was not dehydrated. He seemd to pull through it well and we did not have to give him a shot this time, although he had a virus once and I did indeed give him an injection. My daughter is small for her age and has a very sensitive digestive system. For her to be able to keep the medicine down orally for a 24 hour period was quite an accomplishment, and the doctors told me to continue on her normal schedule, but to triple the doses. Yesterday morning, she started having trouble with the oral meds, so I called the pediatrician who said to bring her right in. We rushed to his office, with Solu-Cortef in hand and it turned out she had an ear infection on top of the viral infection. I gave her the shot there in the pediatricians office and we started her on antiobiotics. My mistake was not taking them to the pediatricians office the minute they got sick-but I am a stay at home mom with 3 babies, and we have dealt with viruses before so I preferred not to drag 2 vomiting children and an 8 month old baby to the doctors office if I could help it. I had the pediatrician tell me yesterday that I would have to give her a few more injections, one every eight hours until she was better, and the endocrinologist disagreed with that . He said she should try to go back to her oral Cortef if possible. Sometimes having too many doctors opinions can complicate matters, so next time I will probably just give the injection and ask questions later. I was not allowed to being either of my CAH children home from the hospital until I could show the doctors I knew how to give an injection. I have done it before. And by the way, I am one of those parents who almost lost one of their CAH children. When my son was born, he was not diagnosed for 10 days and by the time we got him to the hospital, he was minutes away from cardiac arrest. I tend to run to the doctors for a hang nail, especially when it comes to my children. I appreciate all the advice and support I get from this message board. But I take offense to the suggestion that I would play roulette with my children's lives. Thanks again for the advice.