I did not notice any changes when Kyle had been on the IV steroid in the hospital. I must say though...I have noticed that when my kids get sick at times,,,once they have been on the antibiotic for a day, or have been on the mend for a day...they are just little devils! I have friends who say the same thing when they kids start to get better...they've been couped up, sick, hot, not friends to play with, etc. I'd be grumpy, too@!!!!