My husband and I are expecting twins in February. I started dex 8 wks ago . The only thing I'm noticing is some acne and moodiness. I've gained 6 lbs and I am 12 1/2 weeks along. My OB steered us away from a CVS due to the twin factor. We will be having an amnio instead in about 3wks. OUr daughter has had 15 hrs worth of surgery (which we are happy with she needed alot of internal restructuring) and 3 cystoscopies all of which was completed just after her 2nd birthday. The whole ordeal was a nightmare which is why we chose to grin and bear the side efffects if there were any. Thank God it has been this easy so far(knock on wood) I hope I answered your questions. Whatever you do if you decide to go for the dex start as soon as possible(prior to 6wks if possible) . Good luck and God Bless