Dear Susan, Migraines appear to be reasonably common among people with CAH and you may find may be affected also by how your levels are etc. ie, you may get stressed, cortisol gets low and other hormones high and get migraine etc. It is worthwhile to keep a headache/migraine diary to see if there is a consistent time or event-triggered episode link, even if cyclic changes make some difference (obviously not for your brother, but your follicle stimulating hormone and luteinizing hormone, oestrogen levels may all have an effect as well). I get migraines (common and classical), but unfortunately not as you described, so that is all the help I can offer.