Im sorry to hear about your brother. One of my 2yr. old twin girls is a carrier, we found from tests at the endocrinologist pretty soon after birth. It is my understanding that your Dad must have also been a carrier for them to ihave had a child W the disease. I could be wrong but that is my understanding. If anyone else has any info please share it. The carrier questions yare my main concern also. The last time I was online I got onto A message board like this on for carriers & late onset. Im trying to find it sagain you may be interested in that as well. Also miy endo told me it is rare for 2 carriers to marry or should I say the chances are slim was her words. I hope that is correct for my daughters future. Good Luck, LIZ