Thanks so much for all of your responses about the florinef doses (regarding giving 1/2 in morning & other 1/2 in evening). Our endo had been having the whole .1 tablet in the morning. My 4 year-old was complaining too often of a headache in the morning for too long. After reading your postings, I changed her to 1/2 tablet in morning & in evening ... and doing that is what seems to have stopped theses frequent headaches. I had worked with things before to determine if it could be salt needs, fluid needs, glucose needs, or even allergies, but nothing consistently helped. After 3+ weeks of dividing the florinef doses, she's only had one headache in the last 2+ weeks (the day she ran a low-grade fever). Thanks again.