I had a problem with my son's bone age being advanced at the time when the Cortef formula changed. I, too, was in touch with Upjohn and never got much feedback. They did contact my Endo. for some info. about dates, lot #'s, etc. but never really got back to me. Could you tell me who you are speaking with at Upjohn? I need to get in touch with them with Lot #'s (which I don't have....I have to call my prescription Mail Order co. again to get it. As you said, the corporate world is certainly not moving as quickly as we are in trying to correct this. If you can give me any info, please email me at weezie1959@aol.com. Thanks so much. Louise