It has been recommended by our daughters endo to have the blood checked for adrostine, 17 hydro, and renin every month. The reason being she can get out of control(elevated results) thus faster bone maturity. Example her last two blood draws were border line and four weeks later after the second draw her andostine was 140, 17 hydro 9,ooo and renin 8.2.. I switched my daughter to the pill form instead of solution. We live in Alaska.