Kimberly....my endo has always said to stress dose when the temp is over 101.0 degrees OR if the child seems sluggish and tired and stressed out from the illness. I never stress dose my daughter if she just has a cold and seems otherwise okay, smiling and happy and just having a runny nose. But I always did watch her very closely just in case that situation changed and then I would have to stress dose. Isn't it funny how even when they are sick, they still maintain their smiling little faces? They can be so endearing and lovable...... Baiba