Karen (I'll go by 'Kare' ....a family nickname from 30 years ago!) - our daughter was diagnosed just before she turned 4. Her bone age was about 7. She'll be 6 at the end of July and is doing just great on 20 mg/day of cortef. Her bone age is now just about 8....so the acceleration has slowed down. Feel free to e-mail me at kbassler@home.com if you have questions at all. I remember how overwhelming everything was at the time.