Funny you should post this today. My husband and I were just talking about the same possibility. My 4 year old was undersupressed for a year and didn't wet his bed. When they discovered the error and adjusted his meds, he began wetting the bed on a regular basis. My husband had remembered also, when we had to give our Golden Retriever steriods she would have wetting accidents all over the house. There must be something to it. We just don't know exactly what. Thanks for mentioning it. Lynn