Our Endo had us giving florinef in the morning at first then he went to a convention and came back ans told us to change it to 1/4 of a pill in th a.m and 1/4 in the p.m. I notice that our sone has a mean streak when he needs his cortef. But the bed wetting thing is what caught my eye. We would love to pottoy train him at night since he atays dry all day. I guess that I am a little afraid to change meds on my own though.