Thanks for the update. I just made the change last night so I will wait and see for awhile. I would consider splitting it if our endo okay'd it. I think she would. I'm just to nervous about changing his meds without her okay. In fact when I spoke with her about the change I asked if I should give him a dose that night, because he would then go two days without it. I had given it to him on Tuesday morning, Tuesday night she and I spoke and now it would be Wed when he would get it again. She advised me NOT to give it again, not even half, on Tues night because I could cause hight blood pressure. I was glad I asked because I never gave that a thought. Thanks again and I'll let you know. Judy