After switching to the pill about 4 months ago, we have continously lowered my son's dosage. He too is now taking 2.5mg in the am and pm. The reason being that his 17OHP is so low (16) that our endo feels he is definately supressed. The 3x dosage is just too much. We are having his blood draw again in one week to check his levels again. Our endo always said that eventually we would go to a 2x a day dosage. As we all know, it simply depends on each child. Just make sure you have your child's levels checked monthly with each new dosage schedule. Kimberly :)