Just got this from the peds endo listserver that I supbscribe to. If anyone is interested, I suggest that you show it to your endo for input. As the message states, you need to take this to a pharmacist who will take the trouble to compund this correctly. Here is the recipe used in our hospital pharmacy, thanks to John Tourville, our pharmacy director. He has suggested that we have preprinted prescription blanks which has the recipe on the back and the physician signs "Dispense as Written." Some pharmacies will probably not take the time to use the suspending or flavoring agents. Families should be told to make sure they use a compounding pharmacy but to stay away from the high volume pharmacies. This is likely to be worth the effort only for infants where half-tablets do not provide adequate dosing flexibility. HYDROCORTISONE SUSP 2MG/ML STABILITY: 30 DAYS-REFRIGERATOR BATCH SIZE: 100ML Hydrocortisone tablet 10mg 20 tablets Ora-Plus 50 ml Ora-Sweet Q.S. 100ml LABELLING INSTRUCTIONS: Hydrocortisone Suspension 2mg/ml Shake well and refrigerate, Expiration-30 days INSTRUCTIONS: 1. Crush tablets in a mortar, Grind to a fine powder. 2. Add small amount of Ora-Plus and triturate until a uniform mixture is obtained. 3. Add additional Ora-Plus and triturate. 4. Transfer to amber bottle 5. Q.S. with Ora-Sweet REFERENCE SOURCE: Fawcett JP. Boulton DW. Jiang R. Woods DJ. Stability of hydrocortisone oral suspensions prepared from tablets and powder. Annals of Pharmacotherapy. 29(10):987-90, 1995 Oct. Perrin White, MD Professor of Pediatrics UT Southwestern Medical Center 5323 Harry Hines Boulevard Dallas TX 75235-9063 Phone 214-648-3501 Fax 214-648-9772 Hope this helps for those whose infants are having problems with oversupression on the cortef tablets. Amandasmom