My son is not a salt-waster, so forgive me if I am mispeaking, but I always understood that aldosterone prevented the loss of excessive fluids and salts into the urine. Therefore, salt-wasters (who lack aldosterone) would probably tend to "pee" more often than others, if their aldosterone levels are not well controlled by florinef, or a similar medication. Couldn't problems with bedwetting have to do with the fact that salt-wasters have to "go" more often, so there are many more opportunities for accidents? Again, my son is not a salt-waster and we have never had a problem with bed-wetting, but I specifically remember our endo. asking us if he "peed" excessively or had to get up a lot in the middle of the night when my son was first diagnosed. (He did also confirm later that since my child is NOT salt-waster, this problem wouldn't pertain to us.) It makes sense to me that for CAH children with salt-wasting, it would have to do with florinef medication.