Hi Chris, I checked with my daughter's endocrologist about the dosage. He said that they wanted to go with that lower dosage because of the different way the Cortef pill abosorbs into the system. I myself am still skeptical. I will sit back and wait and see what the bloodwork reveals. Boy, I hope it is good. If it isn't I will not be too happy with her endo. For now, I am just going on trust which is a horrible task for me. So far she has been doing ok with the dosage. What a tense time. Thank you for bringing that to my attention.