Hi Chris, My son made the switch to the cortef pill about 4 months ago. His levels were totally out of whack while on the liquid cortef. After receiving the first test results they indicated a low 17OHP, so we lowered his dosage. We have done this 4 times in the last 4 months, to the point of omitting his mid-day dose. That is why we are so fustrated! I guess the only comfort is knowing that we are not alone. It appears that this is now becomming very common, especially after the liquid cortef recall. Think positive, and please let us know your son's results. Just know that I am thinking and praying for you both :)