That is, even though a child has severe saltwasting CAH, his/her adrenal glands are producing SOMETHING. Some, more or less, than others. Thus, the reason different body masses equate to different dosages to achieve the same result. That is why the latest treatment is to remove the adrenal glands completely to create a pure "Addisonian" state. The theory is that then it would be much easier to treat. I wouldn't want to do this because I truly believe that someday gene splicing will cure CAH. However, I don't believe this will happen until one of our children grows-up very pissed-off that no one is researching their condition adequately, decides to become a genetic scientist and dovelops the cure themselves. By the way: Age: 3.5 years Weight: 40 lbs Height: 41 inches 5mg/2.5mg/2.5mgAndy S.