Chris, Another thing to consider is that the dose that was prescribed two tests ago may have been WAY too much and over suppressed him so much that, even with this amount of reduction the test doesn't make much of a change. Since I don't think that the tests can measure below a 0 reading, <5 is probably the lowest it can go. When my son was way under suppressed they put him on 10mgs as a way to quickly bring his OHP levels down and stop his rapidly advancing bone growth even at the risk of over suppression. After a couple of med tapperings his OHP level was <10. We then lowered it two more times to the dose he is on now (8.75mg)and we came in at an OHP level of 163. I know that each child is different and requires a different amount of meds to keep them in control, but for my child, 10mgs was a dose used to deliberately oversuppress him in an attempt to gain rapid control. He is now maintaining a good level at 8.75. Perhaps the 5 mgs is not so low after all. Your child is 27 months old and my son is 5 years old. Your son weighs 35 pounds and mine weighs 48 pounds. His height is 46" while your child is 35 inches. Your son's body surface area is much smaller (as it should be at 1/2 the age) than my son's. I don't know where I am going with this except to say that the dosing that we were used to when on the liquid is totally irrelivent here and we have to basically start from scratch. Since the active meds were being captured in the crystals in the liquid form we may have needed 15 mgs in order to actually net 5mgs. This went on for 2 years since the formulation changed in July of 1998. Since your child is just over 2 years old, this says that he was on the liquid form since he was born and that he was born just at the time of the formulation change so you are used to the high doses, as was I. Even some of the doctors are having a tough time adjusting to the switch. They are still oversuppressing the children by trying to compare the dose of liquid to the pill. We will be going in for another endo appt. on Friday and will have bloods drawn again. I will now see if he is maintaining a good level on this dose or if we have to change yet again. I know your frustration Chris, just hang in there and see what happens at the next check up with the lower dose. After a couple of weeks you may begin to see a big difference in his appetite. It should slow down a bit. You may see some of the Chusinoid symptoms going away and you may begin to see your child's old personality returning. Seeing these things happening may help you feel better about the seemingly low dose. The fact that your son's bone age is in line and his health and growth are good should also serve to calm your nerves and show that you are on the right track. You seem to be following the same track that that we were on for a while. It does get better. I wish you good luck and will keep you in my prayers.