I totally understand that feeling in the pit of your stomach when your child is away.  My daughter is 12.  We have dealt with the sleepovers for quite a few years now.  I make sure the parents know that she takes medication and that they will remind Kristin at bedtime to be sure she has not forgotten it.  I also make sure they know that if she should become ill or hurt I need to be contacted immediately.  Of course, these sleepovers are always close by and I could get there quickly if necessary.  The really big test came when Kristin was invited to go to North Carolina with a friend for 3 days after Thanksgiving.  It was approximately 5 hours away from me, so I knew I could not get there in an emergency.  First of all, I would not have let her go if I did not feel comfortable that the adult in charge could handle any situation which would have come up.  The friend's mother happens to be a close friend of mine and she is a pediatric respiratory therapist.  You may think that I would be comfortable with her because of her profession - to the contrary, I knew she had seen some pretty critically ill children before and was afraid that she might look at Kristin and say she didn't look "that bad" and maybe allow her to "sleep it off" if she had been sick.  What I did was to meet with her before they left and be sure she had all the emergency numbers - mine, endocrinologist, pediatrician, local hospital there in NC, etc.  I explained what signs to look for if she was ill - what was serious for Kristin - and gave her the solu-cortef and made sure she knew how to administer it.  Remember she works with pretty seriously ill children each day, so she initially thought I was going a little overboard, but when I finished my "lesson" she understood my fears and the seriousness of CAH.  Needless to say, nothing happened when they were gone and in the end it was good for Kristin and for me for her to go.  I can honestly say I would not have been ready for this if she was younger.  I think at the age of 6 I did let her do sleepovers and that was a good start.  Sometimes I wonder how I will ever make it though her college years when she will be away from home!