My heart breaks for you. My son and I went through the exact same situation just about a year ago. He was using the liquid cortef and it was not working. His bones aged 4 years inside of 1 year. He was going into puberty and all that that brings. I know how horrifying it must be for you. Nobody can understand what it's like unless they have actually seen it happen. Your sweet little child becomes a restless teenager overnight. The hormones are raging and there is NO outlet for them. How hard it is for a parent to watch her little child experience something so powerful as to make his body change as well as his personality. My son developed pubic hair (he is now 5 years old) and he gets so down on himself he says things like "I'm just a jerk" or "I know you hate me" or "I wish I were in heaven". It breaks my heart to hear that you are going through it too. It has improved a bit since he began a growth hormone treatment, but it is like chasing your tail to be administering the proper amount of meds. His growth is increased due to the GH so we have to adjust his meds frequently. The good side is that I am sure his depression is related to his feeling different AND the testostorone raging inside him with no outlet. At least when they are in their teens they have their friends to talk to about it, or at least can read information on their own. These little boys can barely read at this point. I know your frustration and have spoken to a child psychiatrist about it on a number of occassions. I would love to talk to you further if you would like. You can email me anytime. I hope knowing that you are not alone gives you the renewed hope that you need to get through this. It's impossible to explain to people how it affects every aspect of your lives and rocks the very core of your abilities to be a good parent. To yell at him for his inappropriate behavior only brings more frustraion as he is acting on hormone NOT on a personality flaw. It destroys his confidence and renders him depressed and feeling even more isolated. I only allow him to talk to ME about some of the "fantasies" he experiences and I can assure you that I would rather have my finger nails pulled out by their roots than listen to some of the mature subjects he broaches. The only saving grace is that he doesn't know everything and still has the power of innocence to protect him from some of his urges and thoughts. The big challenge for me is to try to keep a straight face whenever he says something shocking or funny. I lost my composure once and he began to cry and say that he was stupid and wanted to die. I can only assume that that is what you are going through and I know how your world must crumble around you as you listen to those words. I felt that I had failed him as a mom and that if I just tried some other way I could help him. There is no way to erase the images and urges that he has already experienced, but if they put him on Lupron injections they may be able to stop, and possibly reverse puberty thereby adding some time on before his bones fuse and growth stops all together. It is important to begin his treatment as soon as possible however, because time is of the essence. Email me and I will send you my phone number so we can talk mother to mother. I wait with open arms.