Have any of your children experienced side effects of Cortef even when the blood work says that they are not oversuppressed?  My daughter had a crisis 4 years ago at age 5, and her CAH was very difficult to control afterwards.  Her dosage went up a lot, and she had the moon face and weight gain that you would expect.  Her test results finally showed oversuppression (<10) so we eased off the Cortef.  She continued to gain weight even with blood tests showing good control (~200).  She was very active during this time, swimming daily and running.  Her appetite was insatiable, with stomach growling and pain (not boredom eating). 

Last spring our endo and I had a big talk about the long term effects of the extra weight and she agreed that we needed to do something.  Claire's latest numbers were good, but the doc agreed to a fairly drastic cut (33%) in her daily dose to see if we could oversome the sensitivity she seemed to have to the Cortef.  We saw the difference in days.  Claire wasn't hungry, had better energy (the opposite of what we expected) and immediately started losing weight and growing like crazy.  By the end of the summer her 17-OHP went up to 2000 so we did a very small increase.  Her latest numbers are great and the swelling and insatiable hunger haven't returned.  She looks like a different child.  Have any of you experienced this kind of oversuppression even when the blood tests looked good?