I don't know if I will be much help or not but I will try. My husband has CHF -viralizing non salt wasting. He has been on the same dose of medication since he was 5 years old. He is now 40. He takes 35 mg of Cortef daily. I believe they attempted a change to that years ago, before my time, and were unsuccessful. He has been stable on this dose for years. We live in a small community were there is not much knowledge of CHF so we are depending on the good lord to watch out over him!! Hope this helped.Cindy