Yikes! I don't know what to tell you, Beth, except that you MUST convince your son that if he continues to not take his medication, he could very likely DIE. There are others on this very board who have lost young adult children (one lady lost her son - who was 21 I believe - in very similar circumstances. Perhaps your son doesn't really believe that it is all that serious??? Maybe talking to some other young adults would help (you know about the other CAH board for those with late onset CAH?? There are several younger people with CAH there). If he DOES realize that death is a distinct possibility, then perhaps his apathy with life needs to be addressed: is he suffering from signs of severe depression?? What is he so angry at?? Maybe he needs to see someone for his mental health - to deal with his denial of the CAH, if nothing else. I don't know what else to say, except that I will keep him (and the rest of your family) in my prayers. Please let us know how he's doing.