I will keep your daughter in my prayers. Until you find out for sure from the doctor, you can roll the med vial back and forth between your palms briskly and it warms it up rather quickly. I have noticed a BIG difference in my son's injections when it is warmed and when it is not. As far as the burning sensation goes, make sure that the PICC line is not stressed or bent in any way before injecting the meds. It usually burns if the meds somehow come back out the puncture site to the surface. Good luck.