I will have to find it. I copied it from a web page quite a while ago to word and this is how it copied to word: FIGURE 4-4 Circadian rhythmicity of steroid production and major stimulatory factors. Aldosterone and cortisol and their respective major stimulatory ACTH factors, plasma renin activity (PRA) and adrenocorticotropic hormone (ACTH), demonstrate circadian rhythms. The lowest values for all of these components are normally seen during the sleep period when the PRA need for active steroid production is minimal. ACTH levels increase early before awakening, stimulating cortisol production in prepara- Aldosterone tion for the physiologic changes associated with arousal. PRA increas- es abruptly with the assumption of the upright posture, followed by an increase in aldosterone production and release. Both steroids Cortisol demonstrate their highest values through the morning and early after- noon. Cortisol levels parallel those of ACTH, with a marked decline Morning 6 AM Noon 6 PM Morning in the afternoon and evening hours. Aldosterone demonstrates a broader peak, reflecting the postural stimulus of PRA. It just seemed to go in all higgledy piggledy and I cannot remember where the URL is. I'll try finding it again but it was a simple medical paper on a page where you have to scroll left to right and up and down to finf eveything! I therefore just copied the little part I needed and then pasted it to word and corrected it. But it had all this data on the page also that looked quite technical. I'll try later and post her if i find it. Val