"I am sure that Pharmacia Upjohn is a much larger and more sophisticated company than this New Zealand group."

Lol!!!  More suffocated ya mean!  Hopefully the people she forwards this to will be able to better answer the query!  I mean this woman is wasted in this job if she knows all she does about our kid's but is not effecting changes such as you wrote about within a drug company that she now works for!  Talk about ironic... I mean it takes a parent to write when they have fully qualified Doctors there and know this stuff!

Sorry I did not see this b4 I replied to Shauns post above about time release.  I think 6 hours would be about right as I think anything longer is confusing matters.  I was just thinking to dose at 2pm what would be needed at 3am also to kill two birds.  Maybe we can technically have the four daily doses but in the form of two daily tablets in the way I described above?   One dosed at say 7am that acts immediately but contains a sustained release inside to release it contennts at say lunch time.  (4 hours) and then another at dinner time to have a sustained release pellet that releases at 3am?  Then that way we only have two doses to remember!