AdinaHI have been completely unmedicated throughout my life, up until the past week. I now require Cortef 3 times a day, the same as my children. I have exon 4 and exon 7 mutations, which would classify me as a simple virilizer, although I present as a non classical (genotype does not match phenotype). I was originally left handed, and then changed by my teacher in primary school to write and cut with scissors right handed. I manipulate small objects (keys and things that require precision) with my right hand, and do things that require strength with my left (usually).
My IQ was tested at two points in my life; once by a friend of my mother’s who was studying to become a psychologist, and then again later in life for a reasonably similar situation. At both times it was noted that my quotient was slightly higher than average, as was my non affected, right handed sibling. Both my unaffected sib and I were in advanced and honors English and literature, courses and excelled in foreign language; she in Spanish, and I in French. In fact, we both skipped a level a piece in college language courses, and I tutored three level two juniors during my freshmen year in college. My sister was also excellent at algebraic equations which I could muddle through, but was attentive enough to pull an "A" average (usually) with an occasional "B". However, it was noted that Geometrical math was more my forte, and I loved geometry because it was something that I was finally better than my older sister at.
I graduated high school in the upper third of my class, as did my sister, and I pulled a higher GPA than her in college, and even had scholarships (which she did not).
Our 8 year-old unaffected daughter has had several tests at school that have placed her in the upper reading level (she just finished Harry Potter book 3... remember she’s only 8), and is in the average math level. Our SW CAH son just turned four, and our pediatrician told us he tested out at 5 years and 3 months. He is primarily left handed, and better at math than English and language skills, but he is still advanced at both for his age. He is learning to sound out words phonetically. Savannah is too young to be tested, and we will not know her "handedness" until she is about two years of age. She is seven months, crawls well, has begun to pull up on things, and is beginning to talk.
My husband, on the other hand, is only a double carrier (intron 2 and exon 7 on the same allele), and is right handed. He had some trouble in school with language arts, and still grapples with his vocabulary. He is very good with technical things though such as trouble-shooting electronics (robotic cameras to be specific). He made average grades, and has what I would classify as average intelligence, with moderate linguistic disabilities. His problem in school was largely due to a lack of motivation based on traumatic events in his life during that time period (namely his parent’s divorce).
Just remember that an old marketing tool is to sway numbers and data to fit your conclusion, so they could have discarded a few of the results to technically state that persons with CAH have learning disabilities. I’m not saying that it’s not possible... of course it’s possible. Anything is possible. I’m just saying that they should reformulate their Venn diagrams because it should not be an "all or nothing" blanket statement. Personally, I feel my family blows the "all or nothing" theory out of the water.