I wouldn’t advise changing without your endo’s approval. I think if you really believe that your son would benefit from this kind of schedule you need to prove your point with your endo. Send him/her all the articles. Also send the circadium rhythm curves with current schedule superimposed on it and then proposed schedule so he/she can see the benefits of mimicing or dosing more closely to the natural rhythm. (Laura K helped us with this one!) Write a persuasive letter stating you could have your son tested in 6 weeks to make sure all is well. We have seen great results. Good luck! Julia