re: re: Cortisol--exercise---waking up early.
Aug. 6th, 2002   12:57am

Here is the link again and some sections of what it says:

"Background: 3-beta-hydroxysteroid dehydrogenase (3B HSD) deficiency is a rare genetic disorder of steroid biosynthesis resulting in decreased production of all 3 groups of adrenal steroids, which includes mineralocorticoids, glucocorticoids, and sex steroids. Decreased mineralocorticoid secretion results in varying degrees of salt wasting in both males and females, and deficient androgen production results in ambiguous genitalia in 46,XY males. Much heterogeneity exists in the clinical presentation of this disorder. Although first described in male infants with ambiguous genitalia and severe salt wasting, 3B HSD deficiency also occurs in 46,XX female infants (who may have mild clitoromegaly) as well as in older patients who present with a milder or, so-called, late-onset variant."

Read more here:

http://congenitaladrenalhyperplasia.org/mb/index.php?msg=0216430430&forum=main

Ask your Doctor if he/she has known or treated anyone else with mild 3 beta locah and had them have an healthy pregnancy to full-term without any problems and no daughter born with masculinized or virilized genitalia?  Perhaps they can reasure you in this way that they have dealt with a few and had no problems.

Dhea is a weak androgen but nevertheless an androgen and in high enough amounts may cause problems for baby girls.  This is mentioned in the article at the above link.   

Anne-Marie
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