In fact his growth spurts have been such, that even when we switched from 15mg on conventional dosing per day to 15 mg on the circadian dosing, he grew so much in such a six month period (in contrast with how he was growing before this) that infact we have had to raise his dose and spread it out over FOUR doses.  Something I wanted to do anyway.  In fact if anything he needed four times a day dosing more than a child with much less severe deficiency would have because of the fact that really, he could have been hitting a low much sooner than a late diagnosed child may do.