Thanks for all the responses. I’m quite confused again about few things.

1)  From the reference ranges I understand that they are different for different ages. Therefore why the target of 500-1000 across all age groups ? I agree that we do not aim for perfectly normal levels and a higher than normal level indicates good control. But higher than normal for the relevant age group I would presume ? In this case if the higher end of the range is in the 100 then a high 100 would indicate better control would it not ? If dosage is adjusted to body surface area then it should and would reflect the way cortisol is produced in a normal person i.e based on weight and therefore age . Presumably that is why reference ranges are different for age groups. So I really do not understand why the 500-1000 range is acceptable for any and all children to indicate good control ?

2) Anne - Marie , the blood work for done at Dr.New’s office AFTER I gave the morning meds at 6 am. It was done within about 3 hours I would say.  If the meds are working as they should then after allowing a reasonable amount of time for it to be absorbed by the body, the 17-OHP should be within acceptable ranges for a CAH child is it not ? Does that not indicate then that the meds are doing their job.

3) Shouldn’t there be some kind of a norm, i.e blood work to be done before or after meds and then based on that the values should fall in a certain range.

Our endo said it does not matter if I do the blood work before or after meds. He would just interpret the results accordingly. Dr.New’s office asked us to give  her morning meds at 6 am and then report for blood work.

Thanks,

SueG