you might want to look into this ....

 

Protocol Number: 89-M-0006

Title: Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Controls

Number: 89-M-0006

Summary: Magnetic Resonance Imaging (MRI) unlike X-rays and CT-scans does not use radiation to create a picture. MRI use as the name implies, magnetism to create pictures with excellent anatomical resolution. Functional MRIs are diagnostic tests that allow doctors to not only view anatomy, but physiology and function. It is for these reasons that MRIs are excellent methods for studying the brain.

In this study, researchers will use MRIs to assess brain anatomy and function in normal volunteers and patients with a variety of childhood onset psychiatric disorders. The disorders include attention deficit disorder, autism, congenital adrenal hyperplasia, childhood-onset schizophrenia, dyslexia, multidimesional impairment syndrome, obsessive compulsive disorder, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infection (PANDAS), stuttering, Sydenham’s chorea, and Tourette’s syndrome.

Results of the MRIs showing the anatomy of the brain and brain function will be compared across age, sex (gender), and diagnostic groups. Correlations between brain and behavioral measures will be examined for normal and clinical populations.

Sponsoring Institute:

National Institute of Mental Health (NIMH)

Recruitment Detail

Type: Active Accrual Of New Subjects

Gender: Male & Female

Referral Letter Required: No

Population Exclusion(s): None

Eligibility Criteria:

Children (ages 4-18) who are healthy (without neuropsychiatric or medical conditions) and patients with specific diagnoses including Attention-Deficit/Hyperactivity Disorder, Childhood-Onset Schizophrenia or Psychotic disorders Obsessive-Compulsive Disorder of auto-immune origin, and Congenital Adrenal Hyperplasia.

No pregnancy, implanted pacemakers, surgical clips, or staples.

Special Instructions:

This is not a treatment protocol.

Keywords:

Autism

Dyslexia

Magnetic Resonance Imaging

Attention Deficit Hyperactivity Disorder

Twin

Childhood Onset Schizophrenia

Obsessive Compulsive Disorder

Sydenham’s Chorea

Tourette’s Disorder

Klinefelter’s Syndrome

Recruitment Keywords:

Congenital Adrenal Hyperplasia

Twin

Conditions:

Autoimmune Disease

Congenital Adrenal Hyperplasia

Healthy

Mental Disorder Diagnosed in Childhood

Neurologic Manifestations

Investigational Drug(s):

None

Investigational Device(s):

None

Contacts:

Patient Recruitment and Public Liaison Office
Building 61
10 Cloister Court
Bethesda, Maryland 20892-4754
Toll Free: 1-800-411-1222
TTY: 301-594-9774 (local),1-866-411-1010 (toll free)
Fax: 301-480-9793

Electronic Mail:prpl@mail.cc.nih.gov

Citations:

Quantitative magnetic resonance imaging of human brain development: ages 4-18

Sexual dimorphism of the developing human brain

Quantitative magnetic resonance imaging of the corpus callosum in children and adolescents

If you have:

• Questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.
• Technical questions regarding the Clinical Center web site, please contact the Department of Networks and Applications, CC.