re: Doctor says in CAH loss of height is unacceptable and preventable.
Oct. 26th, 2002   3:40pm

Bone loss or bone immaturity does seem to have been acceptable in the past.  However, GH deficiency is not something that a CAH child has a problem with, and if Doctors controlled children a little more conscientiously (without additional drugs which can in effect accelerate not just growth, but also pubertal status---thus eventual short stature) and check "each" corticosteroid dose in the childs day, they will achieve near  "normal"  height and weight gain for children.  That and more tests for children to check that they are always on track where it regards the above.

Some Doctors in the past were monitoring some children 6 monthly and not running adequate blood tests, or not taking 24 hour profiles to be sure of "each" dose in the day.  Because "each" dose is excreted within 8-12 hours, a test at one part of the day does not give you a reading as to whether each individual dose was right.  This is not something that Doctors should be guessing at.  They need concrete proof in the way of bloods that are founf to be in the normal ranges taken "before" each dose to make sure that the last dose given was correct or not over shooting the mark. 

It is sad that some Doctors are turning to GH as a means to try to correct the problem when they could be looking at exactly what is causing the deficiency in the first place.  You cannot say that you have tried to control a CAH child and their growth if you have not looked at 24 hour profile for each child that comes along that is growing slow or atleast studied the way cortisol is normally produced in the adrenals and then dosing as per the normal production.  CAH children are meant to have corticosteroid where they are lacking it.  NOT as steroids are traditionally given to people who only take them short term.

When Doctors gel with that and adhere to those basic requirements, CAH children will grow pretty well all on their own accord.

Anne-Marie
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