Carol M.I think there has been a shortage of Solu-cortef since the fall, though I did get a prescription filled here in November (just to be prepared) and did not experience a problem. This is what the govt website on drug shortages has to say about it. (Solu-cortef is the brand name for the product put out by Pharmacia. The chemical compound itself is called "hydrocortisone sodium succinate.")
If you are having problems getting Solu-cortef in your area, there are injectable forms of prednisone and dexamthesone that can be used as substitutes, though they will not have the same salt-retaining properties as Solu-cortef (something to discuss with the doctor, if a substitute is prescribed).
Good luck to all.
**********************************************************************
http://ashp.org/shortage/methylprednisolone.cfm?cfid=16564903&CFToken=54747913
Glucocorticoids for Injection
30 January 2003Products affected
Hydrocortisone sodium succinate
- Solu-Cortef 100 mg vials (00009-0825-07), 100-mg 2 mL Act-O-Vial in single-vial packages (00009-0900-13) and 25-vial packages (00009-0900-20), 250-mg 2 mL Act-O-Vial in single-vial packages (0009-0909-08) and 25-vial packages (0009-0909-16), 500 mg Act-O-Vial in single-vial packages (0009-0912-05), and 1000 mg Act-O-Vial in single-vial packages (0009-0920-03),
Reasons for the shortages
Hydrocortisone sodium succinate
Abbott’s hydrocortisone sodium succinate products are on nationwide back order due to manufacturing difficulties.1 Pharmacia’s 100 mg products are on nationwide back order due to the implementation of a new sterile product process as well as an increased demand for the product.2
Estimated resupply dates
Hydrocortisone sodium succinate
- Abbott has no hydrocortisone in stock. The company estimates a release date by the end of April 2003 for the 100 mg vials and mid-December 2003 for the 250 mg vials. The company has discontinued production of the 500 mg and 1 g vials.1
- Pharmacia is allocating the 100 mg vials and estimates it will have the 250 mg and 1000 mg vials available for allocation in mid-February 2003 and the 500 mg vials in April 2003.2
Implications for patient care
Hydrocortisone possesses both mineralocorticoid and glucocorticoid activity and is generally considered the first-line agent for treating adrenocrotical insufficiency. Because other corticosteroids primarily have glucocorticoid activity (Table 1), concomitant mineralocorticoid supplementation with fludrocortisone may be required in these patients.4,7,8