Hmmm
Feb. 4th, 2003   12:22am

It’s kind of a catch 22 situation really.  Kind of damned if you do and damned if you don’t.   I guess whatever you choose---let’s give for example you choose no steroids---the body lowering of cortisol will inevitably affect what the Mother’s adrenal glands should be doing.  Now if you can make cortisol, this means the negative feedback is going to cause the pituitary to start producing the stuff inresponse to the babies lack of it surely?  I mean they are protected in utero merely because we can make the stuff for them--but in order to do that, our bodies must be sensing that they need to make extra cortisol to begin with.  This to my mind could theoretically cause an OVER production of the stuff and at the same time, the baby making heaps of androgens would not exactly help either.  That lands you in the same pot as the LOCAH lady really---even if you DON’T have CAH.  If you can make it in part as  a LOCAH individual, then your body has even more of a stab at trying to make the stuff---and that again means higher cortisol levels and pre eclampsia.  

So half the time I wonder if you’d be better off taking enough of the stuff to silence the nonsense---but then I wonder exactly if they know what they are doing or aiming at where cortisol levels for pregnancy is concerned and it must be complete guesswork half the time surely.  Whatever you dose a pregnant woman may be too much in some and not enough in others intially, and whislt the not enough may be ok, inevitable some may over shoot the mark and cause temporary high blood pressure, cause pre eclampsia and put the baby at risk also!  Tricky one!

 

 

Anne-marie
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