I know this was not directed to me, but I have a tip anyhow. Start mixing about 20 minutes before injection time. It takes a while to dissolve. We only went to the ped office once. My best friend is a nurse and gives Julia her injection. I gave it once a few months ago, and she said "never again". Hopefully we will only need them for a few more months. Julia will be 11 in June and has reached her target height of 5’6".