They say that perhaps it is not right to make changes to a germ line, because some of the people who will be affected are not even born yet and therefore cannot give their consent. An even bigger concern is that making changes to germ cells could disrupt the development of the embryo or fetus in unexpected ways. For these reasons, most people feel that germ-line therapy should not be used until we fully understand its long-term effects and have addressed the ethical questions it raised. 

Lol!  I don’t know what kind of argument this would be?  I mean I think as a future decendant, they could sit their feeling angry that they have the actual medical condition that you passed onto them.  I can understand the potential for other things to happen that are a concern thought with this where it concerns disrupting the development of a fetus etc.  Thanks for posting the article Andrew.  It was quite enlightening.

For what it’s worth I think both boys should have the growth therapy or neither should have it.  There should be no preference shown to either really.   I think the child should be giving consent though and fully understand the consequences or side-effects.  problem is, how old is it that they can fully understand these things and comprehend that instead of making them taller, it may do nothing and cause other problems, or may make them shorter in the long run?  

I mean where do you draw the line with such treatment that diversifies from the plain "replacement" of one hormone that is missing where CAH is concerned?  Anything deviating from it is experimental until proven and in a sense should involve informed consent.