I’ve posted here a few times in the past.  My son started having adult body odor and slight acne at 7 1/2.  The first ped. endo. I took him to said he had very mild LOCAH because of his initial bloodtest (17-OHP=119 I think) and the ACTH stim where it went from 383 to 1178.  I took him to someone in Dr. New’s group and they did genetic testing on him and said he was just a carrier and therefore the 17-ohp was from something else.

Now he’s 8 1/2 and his bone age jumped from 8 to 10 in 6 months.  Dr. Voigatzi (at Dr. New’s office) started him on 1 mg. arimidex and said I should do puberty testing.  I heard on the internet that some kids with premature adrenarchy - which is what he would have if he didn’t have CAH - can get very low doses of Cortef.  So I asked her if she would humor me and she gave him 2.5 mg of Prednisone too.

Then  I spoke to a third pediatric endo who is really a researcher and not very versed in dosages etc.  But she said that if his 17-ohp went up, he has CAH regardless of genetic testing - which is what I kind of thought too.  I mean if that’s the hormone that’s out of whack (his testosterone is a little high - 20) than treating that should help right?

Well, is there any controversy about genetic testing vs. blood tests?  If he has CAH do you think the drugs we’re giving him are right?

By the way, I have a daughter who went through puberty early - she started at 8 and got her period at 10 1/2.  Now she has PCO.  Her a 17-ohp is totally normal though. But I always thought it was an amazing coincidence that both of my kids should have similar problems from totally unrelated causes.  The third doctor thought she should get the stim test.   What do you think?

Thanks.  Sorry this was so long.