We saw results in 3 months! We had to sell this schedule to our endo. Go prepared to the appt. I wrote a persuasive paper basically and had all the research papers in hand to give to her. She took about 3 weeks to contact other endos before she said okay. You might want to ask Chris D for some vital info. From home I can post some research papers. Good luck. Julia Oh also, check the archives on this board for circadium rhythm dosing.Julia S