What are the lifetime consequences of circadian dosing? I am thinking of asking my Endo for this for my granddaughter.... She has terrible nightterrors and wakes up two to three times a night wanting milk or juice. She has outbursts of anger and Horrible mood swings. Screams like she is in pain sometimes and in five minutes turns sweet as she can be. She is only three but is making life REALLY tough for us right now and we are wondering if maybe her meds need to be adjusted. Our Endo has not let us know any of the results of her bloodwork and it seems we are not communicating with him thoroughly. I have made a list of question from this site to ask him when we see him next. Thank you if you have any input. Cherry A VERY tired and sleepy grandma.