Jenn - I’ve tried various combinations of dex dosages. I’ve done the .25 one day and .5 the next - I’ve taken up to 1.0 on a daily basis. What seems to work the best for me now is taking 1/2 of a .75 a day (.375).  And taking it in the morning. When I take it at night I don’t sleep as well. .5 was too much for me - my bones were thinning. At 1.0 I looked like a blimp-face. When I took .25 daily I went into crisis - it was too little. Just try different combinations and you’ll eventually find what works best for you.

Susan A.