I think a lot of doctors have this view - better to give medication twice a day to ensure compliance, as regular missed doses would be detrimental to the child’s development.  However research has proved that taking hydrocortiosne at least 3 times a day is more beneficial to the patient and I feel it is worth assuring your child’s doctor that you would be vigilant and comply with taking tablets more regularly to see if he/she would agree to revising the schedule.