Stress is stress... physical stress may be more immediately seen and able to treat, but emotional stress can do all sorts of harsh things to our bodies. It is an individual thing. When I am under a lot of emotional stress I get physically ill and need a solu-cortef shot. I would always error on the side of caution rather than be worried about giving a solu-cortef shot. I actually have had a couple shots this past year because of such huge emotional stress... crying, worrying, all of these "emotional" things can cause problems (fatigue, vomitting, stomach problems, hair loss, etc.) It seems like the solu-cortef helps with emotional stress if I have it before it gets too bad. Just my two cents! Amy