no, as long as there giving so many hours the doctor will tell you how many hours they need to get these meds. I think it may change in every case.My daughter has to take them every 6 hours and my daughter gets her florinef at night. Right before bed. She is very good about taking her meds if were a few minutes late giving them to her she’ll tell us I didn’t take my meds mom she’s only just turning five on Christmas.I’ll pray for your family