My daughter with SWCAH was treated for a bad respiratory virus at age 5. Keep on eye on that wheezing, and make sure your son is not doing the "sucking in of the rib cage" kind of breathing. Did they check him for that? They call it asthmatic. Scary word I know, but that is what happened to my daughter. I woke her at her 5:30 a.m. time for her Cortef when I noticed her breathing was pretty labored. With every breath her rib cage sucked in revealing her ribs. She had a pretty high fever too so we rushed her into the ped. The ped. admitted her into the hospital that morning. Put her on oxygen, Orapred, and gave her the nubulizer breathing treatments. To be honest, I don’t remember keeping her on the Cortef but I can’t remember for positive. My best advice for you is to call your endocrinologist and pass this by him. My rule of thumb since my daughter’s birth is to pass EVERYTHING by her endocrinologist, when it comes to dosing her with different steroids. I don’t leave the hospital or doctors office until they have made a call into her endo. making sure he is ok with the procedure, and what HIS directions are when the orapred has been finished. This is a high dose of steriods. I know this for certain. When a CAH patient is put on high dosages of steriods like in this case you must bring them down gradually. It can be fatal if after the stress dose has been completed that you go back to the normal dose the patient takes daily without weining down. I hate to send off the sirens and panic buttons. Again, this is something you need to pass by your endocrinologist and ask him what direction to take. Sometimes it isn’t that high of a stress dose ect. and you can bring them back down normally. But I know when you add this Orapred it makes it pretty high. AGAIN, ask your endocrinologist. Ask him two things, 1. Should we be continuing the Cortef when we use this Orapred? (sometimes it is a low enough dose I believe that you can. Not a doctor myself. 2. Should I wein my son down with Cortef for the next few days after the Orapred and fever are gone? Let us know how he is feeling! Prayers are with you.