Could you please tell me what Orapred is??  Both my oldest boys have been on cortisone acetate and floudrocortisone since birth and almost 5 mths old.  My oldest son swallows his whole and has been since about 2-3yrs old (before that we crushed them)  he is nine now and my middle son has always chewed his ever since we stopped crushing them for him.  Hope this helps a little with this type of drugs.   Brenda